Persistent Changes in Hormones and Growth Factors Involved in Ageing in Patients That Recovered from Severe COVID-19.

ABSTRACT:

Background

The coronavirus disease-19 pandemic affected millions of people and its long-term impact on the health of survivors is under evaluation.

Objectives

In this study, we hypothesized that severe coronavirus disease-19 could promote long-term changes in the blood levels of hormones and growth factors known to be involved in the regulation of ageing.

Methods

We evaluated 49 patients that recovered from severe COVID-19 and compared them with matched controls that were never infected by the virus. The blood levels of growth hormone, insulin-like growth factor-1, insulin, brain-derived neurotrophic factor, nerve growth factor, oxytocin, ghrelin, platelet-derived growth factor, fibroblast growth factor-1, and transforming growth factor-beta were determined using enzy

SUBMITTER: Cuchi-Cabral A 

PROVIDER: S-EPMC12294000 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature