Surgical vs. Medical Management of Infective Endocarditis Following TAVR: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Infective endocarditis after transcatheter aortic valve replacement (TAVR-IE) is a rare but severe complication associated with high morbidity and mortality. The optimal treatment strategy-surgical explantation versus medical therapy-remains uncertain, particularly given the technical demands of TAVR removal and the advanced age of many affected patients.

Methods

We conducted a systematic review and meta-analysis of studies comparing the surgical and medical management of TAVR-IE. Primary outcomes included 30-day mortality and 1-year survival. Secondary analyses explored microbiological profiles, patient demographics, prosthesis type, postoperative complications, and surgical indications. A qualitative synthesis of surgical explantation techniques and reconstructi

SUBMITTER: Magouliotis DE 

PROVIDER: S-EPMC12295500 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature