A Value Framework for Evaluating Population Genomic Programs: A Mixed Methods Approach.

ABSTRACT: Background/Objectives: Value frameworks are useful tools to explicitly define the dimensions and criteria important for decision-making, but no existing frameworks capture the broad value domains of population genomic programs. Using a mixed methods approach, we aimed to develop a novel value framework for evaluating population genomic programs (PGPs). Methods: We first conducted a targeted literature review of published evidence on the value of PGPs and existing frameworks to evaluate and quantify their impact. Value domains and elements were extracted and summarized to develop a preliminary framework. Semi-structured stakeholder interviews on the preliminary framework were conducted from March 2024 to October 2024 with 11 experts representing 9 countries. A thematic analysi

SUBMITTER: Campbell D 

PROVIDER: S-EPMC12296045 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature