The Influence of Calcium Ions and pH on Fluoride Release from Commercial Fluoride Gels in an In Vitro Study.

ABSTRACT: Fluoride gels are widely used in dental prophylaxis due to their proven ability to prevent demineralization and promote remineralization of hard dental tissues. However, the effectiveness of fluoride release from such gels may be significantly influenced by environmental factors such as pH and the presence of calcium ions. This in vitro study aimed to evaluate how these variables affect fluoride ion release from three commercially available fluoride gels-Clarben, Flairesse, and Lunos. The gels were incubated in artificial saliva of varying pH levels (4.5, 6.0, 7.0, and 7.5) with and without the addition of calcium, as well as in other water-based media-tap water, deionized water, and 0.9% NaCl solution. Fluoride release and changes in pH were measured and statistically analyzed using a mul

SUBMITTER: Piszko PJ 

PROVIDER: S-EPMC12296090 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature