Metagenomics-based analysis of mobile genetic elements and antibiotic/metal resistance genes carried by treated wastewater.

ABSTRACT: Wastewater treatment plants in Tunisia are recognized as key locations for the spread of antibiotic and heavy metal resistance genes among bacteria. Despite the widespread presence of pollutants in these treatment systems, there is still a significant gap in our understanding of resistance dynamics. This study focused on analyzing the bacterial community and resistome-mobilome profiles of the Charguia wastewater treatment plant (WWTP). Using metagenomics sequencing, six samples from the influent, sludge, and effluent were thoroughly examined. Our research findings indicated the prevalence of Proteobacteria and high levels of Bacteroidota, Firmicutes, Campylobacterota, and Patescibacteria. After conducting a species level analysis, we identified important

SUBMITTER: Naccache C 

PROVIDER: S-EPMC12296574 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature