Influence of real-world cue exposure and mood states on drinking: testing neurobiological models of alcohol use disorder.

ABSTRACT:

Rationale

Two prominent neurobiological models of addiction, the allostatic and incentive-sensitization models, have guided clinical research on alcohol use disorder (AUD). While these models are often viewed in isolation, it is plausible these theories are complimentary.

Objectives

Use naturalistic, daily diary reports to determine whether positive and negative mood states influence alcohol cue sensitivity in a clinical sample with AUD.

Methods

This is an exploratory analysis of daily diary data collected from a non-treatment seeking sample with current AUD over two weeks. Eligible adult participants (N = 50) were enrolled in a medication trial for AUD. Each morning, participants retrospectively reported on pre-drinking mood states, alcohol cue exposure, and craving

SUBMITTER: Meredith LR 

PROVIDER: S-EPMC12296835 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature