Blood Pressure Management Pre- and Post-Reperfusion in Acute Ischemic Stroke: Evidence and Insights from Recent Studies.

ABSTRACT:

Purpose of review

Effective control of blood pressure (BP) is potentially a critical determinant in making a successful recovery from acute ischemic stroke. BP is often elevated after the onset of this critical illness, and it is related to both the severity of the ischemic injury and subsequent changes in cerebral perfusion and collateral blood flow. However, recent studies have challenged longstanding assumptions over the safety and efficacy of BP lowering in being able to reduce the risk of reperfusion injury in acute ischemic stroke. This review synthesizes contemporary evidence and discusses the evolving landscape of BP management in acute ischemic stroke.

Recent findings

Three prehospital ambulance-initiated trials of early BP lowering in patients with undifferentiated

SUBMITTER: Liu F 

PROVIDER: S-EPMC12296925 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature