Simultaneous Quantification of Main Saponins in <i>Panax vietnamensis</i> by HPLC-PDA/ELSD Using the Quantitative Analysis of Multi-Components by Single-Marker Method.

ABSTRACT: Background: The Quantitative Analysis of Multi-components by Single-marker (QAMS) method has been developed as an alternative to the External Standards Method (ESM) for the quality control of medicinal herbs. Objectives: In this study, QAMS was developed to determine saponins in the raw materials of Panax vietnamensis using HPLC-PDA/ELSD. Methods: The method was developed and validated. The relative conversion factors F_x were calculated based on the linear regression for HPLC-PDA and the logarithm equation for HPLC-ELSD. The Standard Method Difference (SMD) was determined to indicate the difference in the results of QAMS and EMS. Results: Relative conversion factors (F_x) were determined for each detector to quantify five saponins (gi

SUBMITTER: Ngo TM 

PROVIDER: S-EPMC12298259 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature