Procedural Pain Management in Patients with Cerebral Palsy Undergoing Botulinum Toxin Injection: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

The aim of this systematic review is to investigate effectiveness and safety of sedation-analgesia techniques in controlling pain during botulinum injections in patients with cerebral palsy (CP).

Methods

The Pubmed, Cinahl, and Scopus databases were searched. Inclusion criteria were as follows: cerebral palsy; any type of outcome measure regarding pain and side effects assessment; any type of studies; and English language. RoB2 and Robins-I were applied to assess the risk of bias. Tables and forest plots synthetized the findings.

Results

Seventeen reports were included; most regarded pain control, and ten investigated side effects. Three were RCTs, three were controlled, and twelve were observational studies. Several techniques were used, often in combinati

SUBMITTER: Faccioli S 

PROVIDER: S-EPMC12298486 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature