Explaining <i>Echis</i>: Proteotranscriptomic Profiling of <i>Echis carinatus carinatus</i> Venom.

ABSTRACT: Snakebite remains the most neglected tropical disease globally, with India experiencing the highest rates of mortality and morbidity. While most envenomation cases in India are attributed to the 'big four' snakes, research has predominantly focused on Russell's viper (Daboia russelii), spectacled cobra (Naja naja), and common krait (Bungarus caeruleus), leading to a considerable gap in our understanding of saw-scaled viper (Echis carinatus carinatus) venoms. For instance, the venom gland transcriptome and inter- and intra-population venom variation in E. c. carinatus have largely remained uninvestigated. A single study to date has assessed the effectiveness of commercial antivenoms against this species under in vivo conditions. To address th

SUBMITTER: Javed S 

PROVIDER: S-EPMC12298760 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature