Antibiotic Resistance, Virulence Genes, and Molecular Diversity of Clinical <i>Klebsiella pneumoniae</i> Isolates from Patients of District Hospital in Central Poland.

ABSTRACT: In hospital environments, pathogenic bacteria spread easily and acquire virulence and antibiotic resistance genes. The aim of the study was an evaluation of the genetic diversity of 109 K. pneumoniae isolates recovered from patients of a district hospital in central Poland. The frequencies of genes coding for β-lactamases, efflux pumps, and virulence factors were determined. Genotyping of the isolates was performed with ERIC (Enterobacterial Repetitive Intergenic Consensus) and REP (Repetitive Element Sequence Based) PCR techniques, with 21 and 19 genotypes being identified, respectively. The bla_SHV-1 (92.7%), bla_CTX-M group 1 (83.5%), bla_TEM-1 (28.4%), bla_NDM-1 (16.5%), bla_VEB-1 (11.0%), bl

SUBMITTER: Kot B 

PROVIDER: S-EPMC12298917 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature