Relationship Between Vitamin D Deficiency and Postpartum Depression.

ABSTRACT: Background/Objectives: Postpartum depression (PPD) affects approximately 10-20% of women during and after pregnancy, posing significant risks to maternal health, infant development, and family dynamics. Identifying modifiable risk factors is essential for prevention. Emerging evidence suggests that vitamin D, a neuroactive steroid hormone involved in neurotransmitter synthesis, neuroinflammation regulation, and calcium homeostasis, may play a protective role against mood disorders, including PPD. Methods: The search was conducted through a comprehensive search of the PubMed, Scopus, and Web of Science databases using a combination of Medical Subject Headings (MeSH) and free-text terms including "vitamin D", "25-hydroxyvitamin D", "deficiency", "pregnancy", "postpartum", "depr

SUBMITTER: Apostolidou I 

PROVIDER: S-EPMC12298951 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature