Metabolomic and Transcriptomic Analyses Reveal Changes in Active Components During the Growth and Development of Comfrey (<i>Symphytum officinale</i> L.).

ABSTRACT: Comfrey (Symphytum officinale L.) is a traditional medicinal plant, and its growth period has an important effect on the accumulation of active components. Phenolic acids and flavonoids are the most important active components in comfrey, but their accumulation in comfrey has not been studied. At present, most research on comfrey focuses on its roots. There is still a lack of systematic research on the comparison of active components and biological activities in the aerial parts of comfrey in different growth periods. To explore the influence of the growth period on the active components of comfrey, non-targeted metabolomics and transcriptomics were used to comprehensively analyze the active components of comfrey during the vegetative period, blooming period, and maturity period and

SUBMITTER: Fu J 

PROVIDER: S-EPMC12299076 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature