Macroscopic Evaluation of Poly(3-hydroxybutyrate-co-3-hydroxy valerate), PHBV-Based Nanofiber Scaffolds with Aloe Vera or Honey in Murine Wound Healing.

ABSTRACT: Background/Objectives: The utility of various biocompatible biological and synthetic polymers as substrates to provide structural support, facilitate cell migration, and promote the healing of full-thickness wounds by secondary intention has been studied. This includes intelligent structures that enable the release of natural products or drugs for these and other purposes. In this study, the primary objective was to analyze and compare, from a macroscopic perspective, the individual behavior of the polymer poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), with Aloe vera (PHBV/Av) or honey (PHBV/Ho), in the healing process of a full-thickness skin wound over 40 days in a murine model, in addition to describing the microscopic ultrastructure of the nanofibers. Methods: Two

SUBMITTER: Perez-Galvan JM 

PROVIDER: S-EPMC12299421 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature