Central Contrast Sensitivity as an Outcome Measure in Randomized Controlled Trials in Glaucoma-A Systematic Review.

ABSTRACT: Purpose: Standard automated perimetry (SAP) remains the gold standard functional test in glaucoma, used primarily for evaluating peripheral vision loss. Central contrast sensitivity (CCS) has emerged as a potential early functional marker of glaucomatous damage. This systematic review aimed to describe the different methods used to measure CCS in randomized controlled trials (RCT) involving glaucoma patients. Methods: We searched the MEDLINE, Embase, CINAHL, Cochrane Central Register of Controlled Trials, Epistemonikos, and ClinicalTrials.gov databases on 25 January 2023, and updated the search on 12 February 2025. Eligible studies comprised RCTs that reported CCS as an outcome in patients with glaucoma, suspected glaucoma, or ocular hypertension. No restrictions were placed

SUBMITTER: Sverstad A 

PROVIDER: S-EPMC12299499 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature