AI-CAD-Guided Mammographic Assessment of Tumor Size and T Stage: Concordance with MRI for Clinical Staging in Breast Cancer Patients Considered for NAC.

ABSTRACT: Objectives: To evaluate the agreement between AI-CAD-guided mammographic and MRI measurements of tumor size and T stage in breast cancer patients being considered for neoadjuvant chemotherapy (NAC). Methods: This retrospective study included 144 women (mean age, 52 ± 11 years) with invasive breast cancer who subsequently received NAC and underwent both AI-CAD mammography (score ≥ 10) and pre-treatment MRI. Tumor sizes from AI-CAD contours were compared with MRI using Pearson correlation, intraclass correlation coefficients (ICCs), and Bland-Altman analysis. Concordance was defined as a ±0.5 cm difference. The contour showing the highest agreement was used to compare T stage with MRI using weighted kappa. Results: The mean AI-CAD abnormality score was 86.3 ± 22.2. Tumor

SUBMITTER: Park GE 

PROVIDER: S-EPMC12299520 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature