Nasopharyngeal Carriage, Serotype Distribution, and Antimicrobial Susceptibility of <i>Streptococcus pneumoniae</i> Among PCV13-Vaccinated and -Unvaccinated Children in Iran.

ABSTRACT: Background and Aim: Pneumococcal pneumonia is a major cause of death globally, emphasizing the importance of vaccination, especially in low- and middle-income countries. In Iran, the 13-valent pneumococcal conjugate vaccine (PCV13) is available exclusively through private healthcare systems, resulting in a lack of studies on the prevalence of Streptococcus pneumoniae (S. pneumoniae) serotypes among vaccinated children. This research aimed to explore and compare the prevalence of nasopharyngeal pneumococcal carriage, serotype distribution, and antibiotic resistance patterns in healthy PCV13-vaccinated and -unvaccinated children. Methods: From August 2023 to November 2024, a multi-center, cross-sectional observational study was conducted in Tehran, Iran. This stud

SUBMITTER: Ashrafian F 

PROVIDER: S-EPMC12299737 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature