Retrospective Review of Children Hospitalized for Epstein-Barr Virus-Related Infectious Mononucleosis.

ABSTRACT:

Objectives

Our objective was to investigate the clinical characteristics, complications, and treatment outcomes of Epstein-Barr virus (EBV)-related infectious mononucleosis (IM) in children and to identify risk factors associated with prolonged fever and abnormal liver function.

Methods

This retrospective study included 3006 children admitted to Shenzhen Children's Hospital from May 2009 to April 2024 with suspected EBV-related IM. After excluding cases without etiological evidence and those with underlying diseases, 2660 cases were analyzed. Data on demographics, clinical manifestations, laboratory findings, complications, and treatment outcomes were collected. Logistic regression was used to identify risk factors for prolonged fever and abnormal liver function.

Results<

SUBMITTER: Tian S 

PROVIDER: S-EPMC12299831 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature