Analysis of Scyllo-Inositol in a Wistar Rat Animal Model-A Preliminary Study.

ABSTRACT: Background: Scyllo-inositol (SCI) is a naturally occurring carbocyclic sugar implicated in many biological processes. Studies have highlighted the potential of using SCI in Alzheimer's therapy. However, in order to fully use this compound in the treatment of neurovegetative diseases, its pharmacokinetics must be thoroughly understood. Objectives: We undertook the task of analyzing SCI in a Wistar rat animal model. The aim of this study was to observe the changes in SCI concentration after oral administration. Methods: All rats received 10 mg/kg of SCI as a solution in distilled water by oral gavage. Estimated parameters were based on the serum concentration of SCI observed in six individual rats with regard to time. Results: The first peak concentration appeared

SUBMITTER: Wisniewski K 

PROVIDER: S-EPMC12299890 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature