Regulation of MXene Membranes with β-Lactoglobulin Nanofiber-Templated CuS Nanoparticles for Photothermal Antibacterial Effect.

ABSTRACT: Developing advanced antimicrobial agents is critically imperative to address antibiotic-resistant infection crises. MXenes have emerged as a potential nanomedicine for antibacterial applications, but they suffer from suboptimal photothermal conversion efficiency and inherent cytotoxicity. Herein, we report the synthesis of MXene (Ti₃C₂)-based nanohybrids and hybrid membranes through firstly interfacial conjugation of self-assembled β-lactoglobulin nanofibers (β-LGNFs)-inspired copper sulfide nanoparticles (CuS NPs) onto MXene nanosheets, and subsequent vacuum filtration of the created β-LGNF-CuS/MXene nanohybrids. The constructed β-LGNF-CuS/MXene nanohybrids exhibit excellent photothermal conversion performances and satisfactory biocompatibility and minimal cytotoxici

SUBMITTER: Liu Z 

PROVIDER: S-EPMC12300359 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature