Process Development for GMP-Grade Full Extract Cannabis Oil: Towards Standardized Medicinal Use.

ABSTRACT: Background/Objectives: The industrial extraction and purification processes of Cannabis sativa L. compounds are critical steps in creating formulations with reliable and reproducible therapeutic and sensorial attributes. Methods: For this study, standardized preparations of chemotype I were chemically analyzed, and the sensory attributes were studied to characterize the extraction and purification processes, ensuring the maximum retention of cannabinoids and minimization of other secondary metabolites. The industrial process used deep-cooled ethanol for selective extraction. Results: Taking into consideration that decarboxylation occurs in the process, the cannabinoid profile composition was preserved from the herbal substance to the herbal preparations, with wi

SUBMITTER: Costa MDC 

PROVIDER: S-EPMC12300620 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature