Caffeic Acid and Erythromycin: Antibacterial and Synergistic Effects on Staphylococci.

ABSTRACT: Background: Antibiotic-resistant bacteria, especially Staphylococcus species, are a growing concern in healthcare settings and infections caused by multidrug-resistant strains are difficult to treat. Therefore, it is imperative to explore new treatment methods for these infections such as combinations of natural compounds with antibiotics. Methods: The main objective of this study was to investigate the antimicrobial activity of caffeic acid against staphylococcal strains. The viability of bacterial cells and half maximal inhibitory concentration (IC₅₀) for caffeic acid were also examined. The minimum inhibitory concentration (MIC) of the caffeic acid was determined using a serial microdilution method. To study the combined effect of caffeic acid and erythro

SUBMITTER: Kepa M 

PROVIDER: S-EPMC12300647 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature