Novel and Potential Photoprotective and Tyrosinase Inhibitory Effects of <i>Tetrastigma erubescens</i> Extracts: Evidence from In Vitro Assays and Computational Approach.

ABSTRACT: Tetrastigma erubescens, a native medicinal plant of Vietnam, has long been used in folk medicine to manage various diseases, including skin-related issues. However, limited research has been conducted on this herb's bioactivities and chemical composition. This study aims to investigate the chemical constituents and evaluate the anti-tyrosinase activity and UV-A/UV-B absorption capacity of T. erubescens extracts, highlighting their potential as natural sources for skin-whitening and sun protection agents. In vitro assays demonstrated that the ethyl acetate (EA) extract of T. erubescens exhibited a significant UV-A and UV-B absorption capacity. Notably, this extract showed a strong anti-tyrosinase activity for the first time, with a maximum inhibition rate of 99.2% and a

SUBMITTER: Vu TTL 

PROVIDER: S-EPMC12300742 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature