Design of Geraniol-Loaded Nanocapsules for Use Against <i>Salmonella</i> Infantis: Evaluation in an In Vitro Poultry Model.

ABSTRACT: Background/Objectives: Salmonella Infantis (S. Infantis) is a bacterium that has gained importance in public health over the last decade due to its high pathogenicity and resistance to antibiotics. Therefore, the objective of the present study was to present key considerations for the design and development of geraniol-loaded nanocapsules for its delivery in the drinking water or feed of broiler chickens and to evaluate its potential as an antimicrobial agent against S. Infantis using a standard in vitro microplate assay and a model that simulates the pH and feed conditions of the crop of broiler chickens. Methods: Using a 3^k factorial experimental design, geraniol nanocapsule-based formulations were selected, and their antimicrobial activity w

SUBMITTER: Garcia-Salazar KS 

PROVIDER: S-EPMC12300759 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature