Prediction of Mortality by Clinical Laboratory Parameters in Severe Fever with Thrombocytopenia Syndrome: A Meta-Analysis.

ABSTRACT:

Background

This study intended to fully assess the predictive efficiency of different clinical laboratory parameters for the mortality risk in severe fever with thrombocytopenia syndrome (SFTS).

Methods

We systematically searched the Web of Science, PubMed, Cochrane Library, and Embase up to 13 December 2024 for studies on the association of laboratory parameters with SFTS mortality. Two investigators were independently responsible for the study screening and data extraction, and they assessed the study quality using the Newcastle-Ottawa Scale (NOS). Stata17.0 was adopted for the meta-analyses.

Results

We finally included 33 observational studies involving 9502 participants (1799 deaths and 7703 survivors). The results showed that increases in the viral load (odds rat

SUBMITTER: Yan S 

PROVIDER: S-EPMC12300845 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature