A Metalless and Fungicide-Free Material Against <i>Candida</i>: Glass-Loaded Hydrogels.

ABSTRACT: Background/Objectives: We report the antifungal potential of transition metal-free borophosphate glass-loaded hydrogels (BGHs) with different phosphorus/boron molar ratios (P/B = 2, 1, and 0.5) against Candida species. Candida yeasts pose a significant health risk as they can cause infections, systemic diseases, and even potentially fatal complications in immunocompromised individuals. Methods: The antifungal activity of BGH was evaluated against Candida albicans, Candida tropicalis, Candida krusei, and Candida glabrata using kinetic growth analysis, the agar well diffusion method, the minimum inhibitory concentration, the minimum fungicidal concentration, and scanning electron microscopy. Results: All BGH formulations effectively inh

SUBMITTER: Peiter GC 

PROVIDER: S-EPMC12300885 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature