Metabolomic Profiling of Erector Spinae Plane Block for Breast Cancer Surgery.

ABSTRACT: Background and Objectives: Regional and systemic analgesic techniques, such as erector spinae plane (ESP) block and opioid administration, implemented during cancer surgery, have been shown to influence immune responses and potentially affect cancer outcomes. Surgical stress and analgesic techniques used in cancer surgery-such as regional nerve blocks or systemic opioids-not only affect pain control but also influence immune and inflammatory pathways that may impact cancer progression. To understand the biological consequences of these interventions, metabolomic profiling has emerged as a powerful approach for capturing systemic metabolic and immunological changes, which are particularly relevant in the oncologic perioperative setting. In this study, we examined the impact of the ES

SUBMITTER: Guran E 

PROVIDER: S-EPMC12300947 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature