Role of random blood glucose and HbA1c levels in optimizing glucose tolerance screening in early pregnancy: a retrospective cohort study.

ABSTRACT:

Objective

Random blood glucose (rBG) levels are commonly measured in Japan; however, no standardized cutoff values exist for glucose tolerance screening in early pregnancy. The contribution of glycated hemoglobin (HbA1c) and glycated albumin (GA) measurements to the diagnosis of gestational diabetes mellitus (GDM) remains unclear. Therefore, we aimed to evaluate the significance of these glycemic indicators in early pregnancy for predicting GDM.

Methods

This observational cohort study enrolled pregnant women who underwent initial prenatal examinations to determine their rBG, HbA1c, and GA levels at a rural maternity facility. Clinical data were retrospectively reviewed.

Results

A total of 449 patients were analyzed, comprising 394 with normal glucose tolerance (NGT) a

SUBMITTER: Chigusa Y 

PROVIDER: S-EPMC12301561 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature