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Does a specific age group impact sperm cryobanking efficiency among adolescent and young adult cancer patients?


ABSTRACT:

Objective

Fertility preservation is vital for adolescent and young adult (AYA) cancer patients. Sperm cryobanking is a key option, but age-related factors influencing its efficiency remain unclear. This study evaluated the impact of age on cryobanking attempts, success rates, and disposition outcomes among AYA patients with cancer aged 11-25 years.

Methods

We retrospectively analyzed 298 AYA patients with cancer referred for fertility preservation counseling over 9 years. Data on cryobanking attempts, success rates, and disposition outcomes were stratified by age group (11-15, 16-20, and 21-25 years). Logistic regression was used to assess factors influencing these outcomes.

Results

The mean age was 16.0 years, with leukemia (22.5%), sarcoma (22.1%), and lymphoma (17.

SUBMITTER: Park SJ 

PROVIDER: S-EPMC12301563 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature