Temporal Trends in Cardiovascular Mortality in Underlying Viral Hepatitis: A Retrospective Analysis of Gender, Racial/Ethnic, and Regional Disparities.

ABSTRACT:

Objective

This study aimed to investigate contemporary trends in mortality related to cardiovascular disease and viral hepatitis.

Methods

We conducted a retrospective analysis using data from the CDC-WONDER dataset. Our study cohort consisted of adults aged ≥ 15 years, where both cardiovascular disease and viral hepatitis were identified as an underlying or contributory cause of death between 1999 and 2020. Crude and age-adjusted mortality rates (AAMR) per 1 000 000 population were extracted. Joinpoint regression analysis was utilized to calculate annual percentage change (APC) of each trend.

Results

The overall AAMR exhibited a notable increase from 15.2 in 1999 to 24.9 in 2020. However, a recent decline was observed from 2013 to 2020 (APC: -2.1; 95% confidence inter

SUBMITTER: Sultan W 

PROVIDER: S-EPMC12301567 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature