Conventional imaging techniques plus ¹⁸F-Fluorocholine PET/CT: a comparative study of diagnostic accuracy in localizing parathyroid adenomas in primary hyperparathyroidism.

ABSTRACT:

Background

Currently ¹⁸F-Fluorocholine (FCH)-PET/CT is a choice beyond widely used techniques like ultrasound (US) and technetium-99m sestamibi (MIBI) for primary hyperparathyroidism (pHPT). It remains uncertain how FCH-PET/CT collaborates with those two traditional modalities. This study aims to prospectively evaluate the effectiveness of individual, complementary, and combined utilization of FCH-PET/CT for preoperative localization.

Methods

All participants underwent US, MIBI, and FCH-PET/CT examinations, and eligible patients underwent parathyroid surgery based on surgical indications and patient preferences. McNemar's test compared diagnostic performance between imaging techniques and Spearman's rank correlation correlated FCH-PET/CT parameters with lesion vol

SUBMITTER: Chiu WY 

PROVIDER: S-EPMC12301907 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature