En Face OCT and the Phenotype Characterization of Drusen.

ABSTRACT:

Purpose

To detect and differentiate the various subtypes of drusen and subretinal drusenoid deposits (SDDs) using single-capture en face spectral-domain optical coherence tomography (SD-OCT) imaging.

Methods

This study was a retrospective case series. Sixty-six eyes of 37 patients with evidence of soft, cuticular, and calcified drusen and SDDs were analyzed. Structural en face OCT images were reconstructed using two 40-µm-thick slabs and one 400-µm-thick slab positioned at different levels above and below Bruch's membrane. The various features captured with en face OCT at different levels of segmentation were applied to study and classify the subtypes of drusen and SDDs.

Results

Dot and ribbon SDDs were clearly captured with outer retina slab segmentation. Soft, cutic

SUBMITTER: Voichanski S 

PROVIDER: S-EPMC12302042 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature