Intraoperative Spectrally Encoded Coherence Tomography and Reflectometry (iSECTR) for Ophthalmic Surgical Guidance.

ABSTRACT:

Purpose

We present an optimized intraoperative spectrally encoded coherence tomography and reflectometry (iSECTR) system integrated with a Zeiss OPMI VISU 200 ophthalmic surgical microscope (Zeiss, Oberkochen, Germany).

Methods

An iSECTR scan-head was designed to overcome previous barriers to clinical translation by improving system stability, optimizing optical throughput, reducing reflection artifacts, and adding motorized focus-adjust functionality. The iSECTR imaging performance was demonstrated in in vivo human eyes and during simulated ophthalmic surgical maneuvers in ex vivo porcine eyes.

Results

The optimized iSECTR scan-head achieved a footprint of 19.67 × 30.2 cm (width × length) and a surgical microscope stack height increase of only 6.06 cm. Motorized focu

SUBMITTER: Hecht R 

PROVIDER: S-EPMC12302043 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature