Elevated Intraocular Pressure Immediately after Cataract Surgery and Future Risk of Primary Open-Angle Glaucoma in the IRIS® Registry (Intelligent Research in Sight).

ABSTRACT:

Objective

This study evaluated associations between postoperative intraocular pressure (IOP) after cataract surgery and the future risk of developing primary open-angle glaucoma (POAG) in patients without prior glaucoma, glaucoma suspect, or ocular hypertension diagnoses.

Design

Retrospective cohort study.

Subjects

1 912 101 individuals without prior glaucoma, glaucoma suspect, or ocular hypertension diagnoses who underwent their first cataract surgery in the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight).

Methods

The highest IOP recorded on postoperative days 0 to 2 was used for analysis. For Kaplan-Meier survival estimates and Cox proportional hazards model analysis, IOP was dichotomized into normal (≤21 mmHg) and high (>21 m

SUBMITTER: Gim N 

PROVIDER: S-EPMC12302645 | biostudies-literature | 2025 Nov-Dec

REPOSITORIES: biostudies-literature