Genomic insights into bacteriophages: a new frontier in AMR detection and phage therapy.

ABSTRACT: The misuse and overprescription of antibiotics have accelerated the rise of antimicrobial resistance (AMR), rendering many antibiotics ineffective and leading to significant clinical challenges. The conventional treatment methods have become progressively challenging, posing a threat of evolving into an impending silent pandemic. The long track record of bacteriophages combating bacterial infections has renewed hope into the potential therapeutic benefits of bacteriophages. Bacteriophage therapy offers a promising alternative to antibiotics, particularly against multidrug-resistant (MDR) pathogens. This article explores the promise of phages as a potential means to combat superbugs from the perspective of the genomic and transcriptomic landscape of the phages and their bacterial host. Adva

SUBMITTER: Banerjee B 

PROVIDER: S-EPMC12302716 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature