Effects of ischemic conditioning on microvascular reactivity to single passive limb movement in young adults: a pilot study.

ABSTRACT:

Purpose

Single passive limb movement (sPLM) of the lower extremity is a simple and clinically relevant measure of the microvascular vasodilatory response to movement. A promising stimulus to improve microvascular health is ischemic conditioning (IC). We examined whether a single session of IC could improve microvascular reactivity to sPLM in young adults.

Methods

This was a blinded, crossover, randomized clinical trial. Participants were seated in an isokinetic dynamometer that passively moved the knee 90° at a frequency of 1 Hz while superficial femoral artery leg blood flow (LBF) was measured. The absolute and the relative peak changes in LBF were calculated as the difference from baseline. The time to peak was calculated from the start of sPLM to peak LBF. The total area

SUBMITTER: Whitaker-Hilbig AA 

PROVIDER: S-EPMC12302722 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature