Association between outdoor artificial light at night, circadian health, and LDL-C in intracranial artery atherosclerotic stenosis.

ABSTRACT:

Background

Outdoor artificial light at night (ALAN) exposure interferes with sleep-wake cycles, leading to sleep disorders, and disrupts metabolic processes, which are closely interconnected. Disruptions in circadian rhythms caused by ALAN may indirectly contribute to metabolic dysregulation, especially in vulnerable populations such as patients with intracranial artery atherosclerotic stenosis (ICAS). This study aimed to evaluate the relationship between outdoor ALAN exposure and low-density lipoprotein cholesterol (LDL-C) control in ICAS patients, and to investigate the underlying mechanisms.

Methods

We investigated the relationship between outdoor ALAN exposure and LDL-C control in ICAS patients, estimating residential ALAN levels using satellite images. Sleep quality was

SUBMITTER: Yang L 

PROVIDER: S-EPMC12302883 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature