The value of inflammatory indices in the diagnosis of acute appendicitis and prediction of complicated appendicitis: a retrospective study.

ABSTRACT:

Background

Acute appendicitis is a common cause of acute abdominal pain, typically treated surgically, although medical management is also an option. Laboratory investigations play a valuable role in diagnosis and predicting prognosis. We aimed to investigate and compare the effectiveness of indices such as the Systemic Immune-Inflammation Index (SII), Systemic Inflammatory Response Index (SIRI), and Pan-Immune-Inflammatory Value (PIV), all derived from complete blood count, in diagnosing acute appendicitis and distinguishing between complicated and uncomplicated cases.

Methods

We retrospectively analyzed data from 334 patients diagnosed with acute appendicitis and 350 healthy individuals. The SII, SIRI, and PIV parameters were compared between the acute appendicitis group a

SUBMITTER: Yarkac A 

PROVIDER: S-EPMC12302964 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature