The association between Toxoplasma gondii infection and asthma in the United States: A cross-sectional survey analysis.

ABSTRACT: The hygiene hypothesis proposes that declining exposure to microbial influences early in life is implicated in the rising trend of allergy and asthma in high-income societies. Approximately 8% of Americans have been diagnosed with asthma, representing 25 million people, and understanding how the human microbiome affects asthma could help guide exposure recommendations or microbe-based therapeutics. Toxoplasma gondii is a common gastro-intestinal microorganism that may modulate immune function. We used a cross-sectional study design to examine a public database of U.S. residents aged 6-80 years or older from the 2012-2014 survey cycles of the American National Health and Nutrition Examination Survey (NHANES) to construct an ordinal logistic regression model of the relationship between T. go

SUBMITTER: Anholt H 

PROVIDER: S-EPMC12303259 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature