Oropouche fever outbreak in Brazil: Key factors behind the largest epidemic in history.

ABSTRACT: Oropouche virus (OROV) is an arthropod-borne virus responsible for outbreaks of Oropouche fever (ORO) in Central and South America since the 1950s. Herein, we investigated the climatic and socioenvironmental factors contributing to the reemergence of ORO in Brazil in 2024, culminating in the largest epidemic in the country's history. Accordingly, we conducted a modeling study to identify areas with the highest incidence of OROV in Brazil based on confirmed human cases between the 2020 and 2024 outbreaks and socioenvironmental variables. Our analysis utilized Maxent software, a machine learning algorithm for species distribution modeling, along with SatScan software to identify high- and low-risk spatial clusters. A total of 8,258 ORO cases were serologically confirmed in Brazil in 2024 and

SUBMITTER: Lorenz C 

PROVIDER: S-EPMC12303302 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature