Antioxidant potential of tree bark extracts: Insight from the multi-level output of the Antioxidant Power 1 assay.

ABSTRACT: Tree bark is a complex protective tissue that serves both physiological and defensive functions and is particularly rich in phenolic compounds bearing antioxidant, antimicrobial, anti-inflammatory and wound healing properties. The aim of this study was to investigate the antioxidant activity of aqueous bark extracts from 6 European tree species, namely black alder, common beech, silver birch, bird cherry, oak and scots pine using the antioxidant assay Antioxidant Power 1 (AOP1) on a keratinocyte cell line in the light of dermatological applications. The AOP1 assay relies on light-induced intracellular reactive oxygen species (ROS) production that disrupts efflux transport, enabling the accumulation of fluorescent cyanine dyes which can be quantitatively detected by increased fluorescence.

SUBMITTER: Rehrl J 

PROVIDER: S-EPMC12303309 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature