Environmental relevant concentrations of copper sulphate induce biochemical and molecular toxicity in Labeo rohita.

ABSTRACT: Copper is an important element involved in the catalysis of many vital reactions in the body of an organism. However, excessive copper causes cellular damage by accelerating the production of reactive oxygen species and disrupting the physiological reactions. The present research was conducted to determine the toxicological effects including oxidative stress profile, concentrations of anti-oxidant enzymes and genotoxicity of three different doses (0.28 µg/L, 0.42 µg/L and 0.56 µg/L) of copper sulphate (CuSO4) subjected to Labeo rohita for 36days. Micronucleus test indicated a significant (p < 0.05) increase in the frequency of morphological and nuclear changes in the erythrocytes of the treated fish. A significant (p < 0.05) increase was observed in oxidative stress parameters (ROS, TBARS)

SUBMITTER: Naz S 

PROVIDER: S-EPMC12303335 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature