Clinicopathologic Characteristics of Intraglomerular Malignancy in Kidney Biopsies.

ABSTRACT:

Introduction

Intraglomerular malignancy (IGM) is a rare finding, with current data limited to case reports and small, often postmortem, series. This study aimed to characterize the clinicopathologic features of kidney biopsy cases with IGM.

Methods

Renal biopsy cases diagnosed with IGM from January 2000 to June 2023 at Cedars Sinai Medical Center were retrospectively reviewed. Demographic data, clinical characteristics, and pathologic data were collected, and cases were divided into hematologic (HEME) versus non-hematologic (non-HEME) malignancy.

Results

We identified 9 patients with IGM. Five were hematolymphoid in origin, and 4 were from metastatic solid tumor (2 carcinomas from the lung, 1 neuroendocrine tumor of likely lung origin, and 1 from the head and neck). A

SUBMITTER: Lee CYJ 

PROVIDER: S-EPMC12303561 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature