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Sublingual ranulas, is it time for a new classification? A systematic review and meta-analysis.


ABSTRACT:

Objectives

Sublingual ranulas present diagnostic and therapeutic challenges due to their heterogenous clinical presentations. This systematic review and meta-analysis aims to synthesise treatment outcomes and proposes a new classification for this condition.

Methods

Following PRISMA guidelines, a thorough literature search identified studies on patients with sublingual ranulas receiving medical or surgical treatment. Proportion meta-analysis compared success rates among studies using a random-effects model.

Results

Forty-two studies were included, covering 686 endoral ranulas, 429 plunging ranulas, and 16 ranulas extending into the parapharyngeal space. Sublingual sialoadenectomy with or without pseudocyst wall excision showed low heterogeneity and the highest success

SUBMITTER: Lazzeroni M 

PROVIDER: S-EPMC12303724 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature