Geriatric Nutritional Risk Index and mortality in individuals with prediabetes and diabetes: a longitudinal cohort study.

ABSTRACT:

Background

This study examines the relationship between Geriatric Nutrition Risk Index (GNRI) and all-cause and cardiovascular mortality in individuals with prediabetes and diabetes, aiming to guide clinical nutrition management and extend life expectancy.

Methods

We analyzed a weighted sample of 7,640 individuals with prediabetes and diabetes from the NHANES 2005-2018 and the NCI database. Nutritional status was assessed using the GNRI. Survival outcomes, including all-cause and cardiovascular mortality, were analyzed using Cox proportional hazards regression models and Kaplan-Meier survival curves. Subgroup analyses and restricted cubic spline (RCS) regressions were further conducted to evaluate the robustness and potential nonlinear relationships between GNRI and mortalit

SUBMITTER: Qiao L 

PROVIDER: S-EPMC12303801 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature