Occupational therapist-guided exercise increased white blood cell and neutrophil counts during clozapine treatment: A case report.

ABSTRACT:

Background

Moderate exercise increases white blood cells and neutrophils. However, there are no reports on the relationship between exercise intensity and these cells. We observed a patient taking clozapine whose white blood cell and neutrophil counts were borderline. Supervised exercise therapy with an occupational therapist stabilized these counts.

Case presentation

A 50-year-old woman with treatment-resistant schizophrenia was prescribed clozapine. By Day 63, the clozapine dosage had been increased to 450 mg/day. Additionally, she was advised to perform a 30-min walking exercise program 1 h before blood tests. Exercise therapy supervised by an occupational therapist was performed eight times, and self-training was performed five times. Exercise intensity was monitored usi

SUBMITTER: Hinotsu K 

PROVIDER: S-EPMC12303845 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature