Application value of dual-sequence MRI based nomogram of radiomics and morphologic features in predicting tumor differentiation degree and lymph node metastasis of Oral squamous cell carcinoma.

ABSTRACT:

Background

Oral squamous cell carcinoma is a highly invasive tumor. The degree of histological differentiation and lymph node metastasis are important factors in the treatment and prognosis of patients. There is a lack of non-invasive and accurate preoperative risk prediction model in the existing clinical work.

Objective

This study sought to develop and validate a combined model including MRI radiomics and morphological analysis to predict lymph node metastasis and degree of tumor differentiation prior to surgical intervention for oral squamous cell carcinoma (OSCC).

Methods

This study retrospectively included 119 patients which were divided into a training cohort (n=83) and a validation cohort (n=36). To predict lymph node metastasis (LNM) and degree of tumor differ

SUBMITTER: Zheng B 

PROVIDER: S-EPMC12303898 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature