Understanding the research landscape of over-the-counter herbal products, dietary supplements, and medications evaluated for depressive symptoms in adults: a scoping review.

ABSTRACT:

Background

Over-the-counter (OTC) products such as herbal medical products (HMPs) or dietary supplements are a valued part of preventative and supportive self-care for depressive symptoms, but there is a wide array of products available, with differing levels of clinical evidence. It is unclear what the optimal directions for future research in this field are.

Aim

We aimed to explore the size and nature of the evidence base available for OTC products for depression in adults aged 18-60.

Methods

We carried out a scoping review following Joanna Briggs Institute guidance. We searched MEDLINE, Embase, PsycINFO, AMED, and CENTRAL from inception to December 2022, and 10% of the results were screened by two authors and the remainder by one author. We included randomised cont

SUBMITTER: Frost R 

PROVIDER: S-EPMC12303899 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature