Altered functional network topology and connectivity in female nurses with shift work sleep disorder.

ABSTRACT:

Background

Shift work sleep disorder (SWSD) in nurses is highly prevalent and is increasingly recognized for its profound impact on human health. However, the brain functional network topology, which provides a comprehensive map of the brain's information processing architecture, remains partially understood in nurses with SWSD.

Methods

45 nurses with SWSD and 45 healthy controls (HCs) underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan. Graph theoretical analysis was used to investigate alterations in brain functional network topology. Functional network connectivity was further examined in nurses with SWSD relative to HCs. Correlations between network metrics and clinical sleep scores were also examined.

Results

Compared to HCs, the SWSD g

SUBMITTER: Yang HC 

PROVIDER: S-EPMC12303962 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature