Toxicological Effects of Air Pollutants on Human Airway Cell Models Using Air-liquid Interface Systems: A Systematic Review.

ABSTRACT:

Purpose of review

Global air pollution has increased significantly in recent decades mainly due to anthropogenic emissions. This results in elevated concentrations of some airborne pollutants like nitrogen dioxide, ozone, volatile organic compounds (VOCs), and particulate matter (PM). In this review, we aim to provide an overview of the current state of knowledge on the toxicological effects of air pollution on airway epithelial cells, the first point of contact of the air pollutants with the body, using air-liquid interface (ALI) models.

Recent findings

Research on the health effects of air pollution has advanced through studies that take a multidisciplinary approach integrating toxicology, epidemiology, and molecular and cell biology. Submerged cell cultures have been used

SUBMITTER: Navarrete-Aliaga O 

PROVIDER: S-EPMC12304069 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature